|
KMID : 1132720150130040152
|
|
Genomics & Informatics
2015 Volume.13 No. 4 p.152 ~ p.155
|
|
|
Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
|
|
Lent Heather
Lee Kyung-Eun
Park Hyun-Seok
|
|
|
Abstract
|
|
|
|
Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function.
|
|
|
KEYWORD
|
|
|
chromatin state, epigenetics, epigenomics, genetic promoter regions
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|